Understanding DMPK and ADME in Drug Discovery
Understanding DMPK and ADME in Drug Discovery
A compound can work well against an isolated target yet fail to produce the expected effect in an animal study. It may not reach sufficient exposure, may be cleared rapidly or may distribute poorly to the tissue of interest. Understanding these possibilities is central to DMPK services.
DMPK stands for drug metabolism and pharmacokinetics. It...
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